GRA Vacancy at MMU – Biomedical Engineering

1. Project Title: Novel dielectrophoretic morphologies and colloidal behaviours for biomedical applications
2. Abstract:

In this work, the researcher focuses on dielectrophoresis as it has the capability of assembling colloids into forming suspended objects and that while they can be brought into close contact with each other, they can still remain unbounded. Dielectrophoresis refers to the motion of neutral colloidal particles induced by a spatially non-uniform electric field. When subjected to a non-uniform electric field, a neutral particle is polarized and dipoles are established which induce unequal Columbic forces at opposing ends of the particles and the net resulting force causes the particles to move. Dielectrophoresis can be utilized in several biomedical applications including early detection and prognosis of various cancer types, diagnosis of infectious diseases, blood cell analysis and stem cell therapy. However, there are still numerous challenges to be resolved to have DEP-based devices available in the point of care market. They include understanding fundamental physics and behaviors of colloidal particles in different dielectrophoretic (DEP) microelectrode morphologies.In this research, the researcher will explore these morphologies using a variety of microfluidic channels and using suitable DEP microelectrode configurations. The research will involve both, simulations and experimental methodologies. The purpose is to analyze the behavior of bio-colloidal candidates and to investigate suitable DEP configurations for the development of clinical diagnostic platforms which possess high selectivity and specificity. The outcome of this research includes the understanding of fundamental applied physics and behaviors of colloidal particles using different DEP microelectrode morphologies which entails DEP theory, biological colloidal particle or cell modeling, microelectrode designs suitable for controlling such colloids and the control parameters suited to achieve the objective of the diagnostic activity. This would pave the way for further enhancement of existing DEP enabled clinical diagnostic devices, enable rapid and complex assays and bio-colloidal sensors actuated by the DEP force.

3. Number of Vacancies: 2 Masters students (1 funded under FRGS and 1 funded under FRGS/MMU-GRA), Project duration: 24 months (Masters)
4. Monthly allowance: RM1,800 (min) – RM2,300++ (amount varies depending on successful application of MS-GRA RM500-RM800, or MyBrain scholarship)
5. Tuition fees: Waived except for the following expenses:
a. Registration for two subjects (RM250 per subject), deposit of RM500 and smart card (RM50)
6. Requirements:
a. FRGS Funded Applicant: Malaysian citizen with CGPA 2.75 and above and Bachelor’s degree (for Masters) related to Electrical/Electronics/Materials/Bio/Chemical Engineering
b. MMU GRA Funded Applicant: Malaysian citizen or International applicant with CGPA of 3.67 and above Bachelor’s degree (for Masters) related to Electrical/Electronics/Materials/Bio/Chemical Engineering
7. Successful completion of the research will lead to a Masters by Research in Engineering

Interested applicants, please email your complete resume (including any research experience or projects, contact details of 2 referees) and a copy of your academic transcript to
Dr. Aminuddin Kayani (aminuddin.kayani@mmu.edu.my)

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